• The first stage of the reaction is simple tautomerism.
  • The final step of this reaction follows the E2 reaction mechanism.
  • Intramolecular reaction is, of course, vital to the heterocycle formation.
  • The same starting material can be used to form pyrroles or thiophenes.


    References:
  • Amarnath V.; Amarnath K.; Journal of Organic Chemistry, 1995, Volume 60. Issue 2, 301-307
  • Minetto G.; Raveglia L.F.; Taddei M.; Organic Letters, 2004, Volume 6, Issue 3, 389-392