• There are two examples of the E2 mechanism in this reaction.
  • Intramolecular reaction is, of course, vital to the heterocycle formation.
  • The same starting material can be used to form pyrroles or furans.
  • Other reactions involving sulphur reactivity: Kornblum, Mannich, Pummerer, Ramburg-Backlund and Swern reactions.


  • References:
  • Hewton C.E.; Kimber M.C.; Taylor D.K.; Tetrahedron Letters, 2002, Volume 43, Issue 17, 3199-3201
  • Yuguchi M.; Tokuda M.; Orito K.; J. Org. Chem., 2004; Volume 69, Issue 3, 908-914