This base pairing provides a means of duplicating
the DNA during cell division. Each strand of the parent DNA molecule
unwinds, and different nucleoside triphosphates (deoxyadenosine
triphosphate, dATP; deoxycytidine triphosphate, dCTP; etc.) are
paired with the exposed bases on each strand. The free energy of
the triphosphate is used to connect these paired nucleotides into
a 5`-3` polymer, so that each of the parent DNA strands now is paired
with a new strand identical to the one from which it separated.
This replication process is shown schematically
on the right. The result is two daughter helices,
each identical with the parent in base sequence and pairing, and
each containing one of the parent strands and one newly polymerized
strand. The double helix is not only a protection, it is the basis
for reproduction.
Right: DNA is replicated by unwinding the
two strands and building a new complementary strand to each. The
daughter molecules are exact copies of the parent, each with one
of the parent strands. Based and adapted from James D. Watson, Molecular
Biology of the Gene, Second Edition, W. A. Benjamin, Inc. Copyright
© 1970 J. D. Watson.
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